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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6245caaeef18bc385a856ee2fdf0295e3c8545a1745ad9ebe7779e12315e746' 
  AND token = 'XIXeSaraOCIS9GgEektS6jZ58BZd4CrVu0M4Ej9LLPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}