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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e478bb0f1f306fe5bb236256e5809ffcb05c27c4dcf985b10eb0c0e16a80bf' 
  AND token = 'os3rS9wVYV1M3lI8Eu1DNOfcQkfDp8v3zxzfwkd/chA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}