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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd5bdde61127f523bc931dc3ae97117a87f1bcfce1df91ba5c65974bc8906627' 
  AND token = 'nzV4KW/B5/3JVy112RZtW36+TlxNSCv1EYqF3/Io2ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}