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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8325a0c54058ee9536846a04b6652da2e2104793951cd32e9ea41697db02502' 
  AND token = '+XSgBLn/Qd/z1waAzW5eBe/pCVttg79WGSvDx2dKuRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}