SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cdc29933f0e4d3282e172d547cc672cd0475e354b53af4ff7063e02a44e6fe2' 
  AND token = 'HicR3NDkVeTJ4A0lHG1QphQvjc1RD53hjsfFiezTL1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}