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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e66606a73f4bd8abecb0043bd9770b7ea95845d99b3686fece432126202c1d62' 
  AND token = 'RJVPd/Eb0DIq0feH2X4gD6v9CZeh1IXGrY5xACrWNmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}