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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ffe1a6be0c4069fcb1714ff32c9bab8a4f6c55c325ac65ac56bc3380e0bf16' 
  AND token = 'Gev/NdLb9voatZPXDcD2pMNGbgwD6/bFdgN9zXtY9cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}