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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8554129f78ef1cd5d3f45c7ea21d6f23a68aea1b9e526a435059eee65dd7270' 
  AND token = '6LiBjPjOy7aMAWvk/cNzkHbh6NkM1MzlfwCvZZKIvOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}