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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5351c86cacaa3003593c09054e07330ad21d4cfebe1005e109c52da4c35718' 
  AND token = 'Y2TJaTHVxENtgJooXmT0331WCefE5Xr1LMZMOG8l/xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}