SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb90c4344340c203cca0884d81f9f40617e831ff12b80006b776f5571aa35fe2' 
  AND token = '0+z0OkH5xSigeEkyuQl3k+lyjmWSUh8PTI4Ine9KVQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}