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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46247c62a252cdbaa018fd8a3ddf721d75dd45644001da830bd5e884c0b7856e' 
  AND token = 'RuqXPsJvLcP1HlYOFk2Mx8XTh5dcPCjUg5Gkv6ruX2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}