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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e305eb057af9b2a8640d49d013cd82ce80b605203e80fa757dc40ce915a226e3' 
  AND token = 'TAMuVZB9PV48p0Ix/1xvIytrks4M8ssQO0JfWxe2ta4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}