SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fccf3cfd924ea5a85eacebd258b59214eb516838001f1e8b353945a4ad3c648' 
  AND token = 'kcaFXKnPs6txtP1L2tKSbIBhP4XHQdsdjXO3BcOE+Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}