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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bdd56cdb373227a47013e65e138335b8e70b557158cd694a0d50509fbddb4f' 
  AND token = 'xUW1ecDgprQvl3HNe/3+Cj5KZ7MZGPiHynbyV418Iio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}