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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158d74eff2205606b96ec006ee7b5923e18af65f53c0d71de22c8de6df9e8e0d' 
  AND token = 'lIwwh/irLw/nMpX9E/NmaB/8qmY9nWSLDGcPvlFBrac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}