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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9753c72b3367ec19e9b1592d5cd733d29fdeb740c80f442734fa7e5e89441fb4' 
  AND token = 'W16N/JLqUCKHjVfT2b79pgAV1XfofNtSMxrujk8BEoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}