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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dbb4cb07c1a5161d30dc62d58d606a99df4ec0fcf8478b6553b9594ae08c3c1' 
  AND token = 'yqzoM+oz9IiXxVwgR3OTL7QbaoYPrHFISkredn9bJI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}