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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ce5fa802fac2f06dc60c4635285aff92264be7c5ff97be360f2275e211b256' 
  AND token = 'wsWLZ2B3bkxNKTJ4LqBzKy2/33MxSM4hr1Z+28Rd2DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}