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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a6a4c2876ec34a1a63d2f8dc566aa11294073599079a4a22f5762afe5eb21d' 
  AND token = 'e6msfnQ6x50EClxz3mV6nNLjCxaY19agMnkfV2Gviuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}