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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016ce398bc5c9a5d8a434921dca05ed619c5a5174900e6ca2f0b662e0e339722' 
  AND token = 'VFRFur3T45aw6vWZeUr5XDAlYUXdg6sHr/7pZzVlWn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}