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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8c67dc7ce723342357f16e084f66d3728f8296b5199ba388f3fb28311a1838' 
  AND token = '/CK3V6dhKXAf3QiFkhlmfOIfZoYB0GefasXsBim/DBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}