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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd6268544b4c3838cc1c949044f81f117b942d9cd7e187ce494d4c50303d345' 
  AND token = 'o9Ntmv1Alas4xwmD3S1g9q7E7xD4SSFSv7RrIfJtAhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}