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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f03ad78d179d500db5b7a8caa0f64e1f39bb6fe801ac041602b789522eedf1e' 
  AND token = 'k2MhONQcKP+Bqk+U8hfgjkirUFnvmSIF+mkG1m9DfPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}