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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce56d2e0e13da75241bd5bceb1251f92015af51862dc9e6c49ff2882caecfc97' 
  AND token = 'wlUG964lk5wsvmIzQjPJFC1tWOis8i08tWAPoM1PwJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}