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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25db295a9d4d41a731c84acf3a760516f4a159b4974979ab91fbd1b14c1e578' 
  AND token = '1XIK0DIYkAyivYHu3NSp5fJFAohK0h/N2IXVG0pYcCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}