SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14266371d31dc563a7a6d738766dd1e07f4c8d8f798e27ea4cb48a48ebece78c' 
  AND token = 'WzXa5JaXOc0svbxbH0S6qmbV0imPhHdh0VLgxVyj9dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}