SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187ae5df7abfdfeca26380be7522dff9441c0f5f741f9a5ad2587dd99bf20e28' 
  AND token = 'ZQeamYGoiWF9V9/LB1QcvH2e2lW0UUZi988ygkvYdDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}