SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ef03238ff336c6e83b4c80c76d5e233a5abe8246a82bd233bc529ecd66349d' 
  AND token = 'YEMU/6BfyEijVPhRRwcG6kO5HjL7Zo7qu+LlTUl2uLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}