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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe6b4d169c39ecbc902865681eeb5ad9b060b6896830a95c76299af991f81225' 
  AND token = 'lJ7ktUsbEs5LdvNB+tvbN11LKvJ5QUXYcSeJJC552Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}