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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc0efb4887ce3648cba2bd035af475a9a3a70a6ecc716adaa9095d6d56695cf6' 
  AND token = 'UIzJHT8fvEXuWl+DTmYXPd1DA16uQMTwIDQSFQh6Wdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}