SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e26786ae2cf0d465c914b8b62fba8609c9d8fbc5727914b1db976ccb1dde8a71' 
  AND token = 'zNvKUh1vXBQ2Sv5cUjiAJjzfBNB7kL47LQbR1e1Yq/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}