SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33949197310c10d6ce93211c5a30c35410d13ae150f1f89f874b01b22b1c8a78' 
  AND token = 'MUcOzR4DDfWqY6nzftKgAswIb0XGu5jgRY+rP01eLBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}