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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3cad5175758c4298b20282013a35b851fd3423a0f63671a324f0568bd0bb994' 
  AND token = '4P5w/Ee0+0vCgma+p5Q88b4cwcn19Lv4CadxP5C0ezQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}