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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a35f61c41a36be8813a27d97ea02e9e7450e95415b97c5ad086e86154b9344a' 
  AND token = '0MBmvCd7ruj3vxSkbawcWWGnJFCEFkjRY1u54l2XtBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}