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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8a314534f2306f09a38c7d38f21763980f881745f11d3a3cae7f1248f59c00' 
  AND token = 'LBO7yRLucujXVADPsCEV2r0hNDBcsBDDEbVjtZtifmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}