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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b17f2005367c52abe1ecff9fd68b6c87a50c490fbd0e4b3ebeb7bea3b054efae' 
  AND token = 'GkjSBwM2gCo0tsWUTuV8BwAQeYQfVXUjZkKJ2jeUOtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}