SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4de735fc66c5b7648be791f3b0fe56cb19ebf60e20658e69818adf2f7d956df' 
  AND token = '3LwHu09KmDGso/TADLGGernQE3N7kcZUFxc2PU1kZNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}