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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e9c697c26addd79baf22f90be670697cc63a05b8b7eec6baab9b910a7af7a0' 
  AND token = 'F0oJ7beLDBW1AOeBvZYoAeuoPFZdLaedbRo8HqC6pWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}