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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8430a4423b989f433b4d0746f11044338f9253ec3ff46a89f71fd892c8cc44b9' 
  AND token = '+nwTbNg9TkTSfSuLEi6dtr9eE0Bi0wCLfv3rOQ8Ow/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}