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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b26e0c4fc09c6b6035b406c2e3b13ee3c0a6653b48f49fcd5be752f52974285' 
  AND token = '2wEYldxitaazGFzMC0X9DIdRnG50G00u0OUiLr27CR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}