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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68f1234614e9ec6d6924842406d6bdbbdab327d7d087a8ae5e8d28968ae73834' 
  AND token = 'cXqo0Jam/EAkAoJDtnGQh+jjG7KuczFiI0TWDQG+odw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}