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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e6a706dbd23d5a36e0c1c3d90c13b71fe4294244c585fc68d86a1b9cf84459' 
  AND token = 'UoD820FvuktvcCz6tAkwpSoa69L+i6WkeKSLRfq+Vd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}