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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9b08e3ce92f7e87f5027d3327b9d6afa5407189abdabe1be9fd11fc8132bf5' 
  AND token = 'xpChFT2kRxwxPCRfKR8yH/V7NLFgKhKuIJSTvm53Ef8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}