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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb939b3d3c8e7c96e51b81929f93bf6f727f5a978f744b6ed9f2474d15bd2def' 
  AND token = 'gHTXoqdukgg09CeiCnXVuSrnq0gRsEr6428zt0QB0TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}