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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527c685912b0cde47c73c79790a52cb0a37370dcab0e2bd05ac4544113651b25' 
  AND token = 'yZ1bil322YN/t0OFG1NaCHCehk0jB04paIwLb44gKeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}