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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e0a3c2e48e899a6f5a03a3de7d342df7e371f70d757f2af70e3180bf3f3499' 
  AND token = 'NvgxC70Tre18We5R2Z5dyTlZ6q2qo1zqoE7hUg4sOdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}