SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f3183ee8120a897f05b272e3cbdafea3e6718d35be5f8a7b34044c70c603d7' 
  AND token = 'FeoOFeSVJ2UdTCniclSJzF8O50okiaJspS2xxTvOjRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}