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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488e27ff4cc9a2d2afc94504a250d97245ddd53163ddf871278254eddc5812d4' 
  AND token = 'WG9qTKiaUXwL5HbtfcV1v+yb5SeNGnpvKvm5NQho/DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}