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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c93836f56d5e1d74e37dee352a3689ad3ec568d17fdb6421fe1fd13d27235d' 
  AND token = 'X8HRLP+g/9fuvZjRQUczD2/ovFk0RXFU58b/Iud53Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}