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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc97de2b50e7b0160957eceb8e4bc259e54992ba939b2930b545d1c2a67b50eb' 
  AND token = 'OPcWJnSZMi+jCp6W8bkScpe7Q+qE1wjt+CQR8lmUmsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}